Lose the allergy, not your alertness!

  • Sumari Davis Amayeza Information Centre
Keywords: second generation antihistamines


Although histamine plays an important role in the brain (as neurotransmitter) and in the stomach (to aid digestion), its activity at H1 histamine receptors is involved in allergic reactions. When allergens invade the body, histamine is released and causes the small blood vessels to become more permeable leading to watery eyes, a runny nose, sneezing and nasal congestion. Antihistamines work to suppress the effects of histamine and decrease their symptoms. The second generation antihistamines have been developed to be more specific to H1 receptors, thereby reducing the risk of adverse effects such as drowsiness and sedation. This article will discuss the second generation antihistamines in terms of their indications, risks and benefits.

Author Biography

Sumari Davis, Amayeza Information Centre
BPharm Amayeza Information Services