Malaria is a potentially life-threatening disease spread through the bite of an infected female Anopheles mosquito. Although malaria mainly occurs in tropical developing countries in sub-Saharan Africa, South America, the Caribbean, Asia, Eastern Europe and the South Pacific, it is estimated that nearly half of the world’s population is at risk. Despite being preventable and curable, malaria remains a significant global health burden. In 2018, there were an estimated 228 million cases of malaria. Pregnant women and children under five years are at high risk of developing complications or dying from malaria. Of the estimated 228 million people infected with malaria in 2018, there were 405 000 deaths, with children under five years accounting for 67% of these deaths. More than 90% of malaria cases and deaths occur on the African continent.